Clenbuterol
Clenbuterol is a direct-acting sympathomimetic agent and is used as a bronchodilator in the management of asthma and obstructive lung disease. It has an advantage over salbutamol in that its action is longer lasting. It has also been used to increase the development of muscle in cattle. In humans it is effective in reducing body fat, thus its attraction to the body building community. The adverse effects are those of stimulation of the sympathetic nervous system. These are a feeling of nervousness, tremor of the hands, palpitations, headache, insomnia and a rapid pulse rate. In extreme cases there have been cases of acute poisoning with this drug. If any of these symptoms develop, the drug should be stopped immediately and medical advice sought.
Human Chorionic Gonadotrophin (HCG)
Human Chorionic Gonadotrophin is secreted by the pituitary gland and stimulates the formation of Luteinising Hormone (LH). Lh stimulates the Leydig cells to form testosterone. It is this action that is of interest to anabolic steroid users. During a course of steroids there is inevitably some reduction in sperm numbers due to suppression of Follicle Stimulating Hormone. The effects of the anabolic steroid upon the release of Gonadotrophin Releasing Hormone cause this from the hypothalamus. On ceasing the course of anabolic steroids the size of the testes will recover and sperm growth will return to normal providing that the course of steroid is within reasonable limits. The practice of using HCG near the end of a course of steroids to stimulate the testes is baseless and inefficient. At the end of a steroid course, the pituitary gland slowly resumes normal function in most cases and restores the correct balance of hormones. If HCG is used, it takes over the duty of the pituitary gland in starting the recovery of the normal balance. Once hcg is ceased, the testes return to their reduced size and the pituitary resumes its recovery. The use of HCG during a course cannot be recommended, as it only slows the permanent recovery. It has also been associated with the development of gynaecomastia.
clenbuterol,Human,Chorionic,Gonadotrophin,(HCG),sympathomimetic,bronchodilator,salbutamol
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