Clenbuterol as Doping in Sport


One of the preparations, which is often the focus of doping scandals, is called clenbuterol. In medicine it is used in the treatment of bronchial asthma, using its effect to relax the bronchi. In recent years, however, the preparation is extremely popular in fitness and bodybuilding environments and as doping in some sports. It uses its side effects of a stimulant and a fat burner (Fetburner). It is often used as an acute doping, just before sports matches and in sports related to running and endurance, because it simultaneously stimulates the muscles, the central nervous system and improves the respiratory function. This action makes it a favorite doping in sports like cycling, soccer, cross-country skiing, boxing, swimming, athletics and more. In bodybuilding, clenbuterol is mainly used to burn fat and increase pure muscle mass as an alternative to anabolic steroids. As an action, however, he does not have anabolic steroids but belongs to the adrenomimetic group. The substances in this group mimic the action stimulation of the sympathetic nervous system, which is associated with increased overall metabolism, accelerated fat burning and bringing the body to “fight or run” mode. This is why activation of the body in combat readiness is used as a strong stimulant by many athletes.

Searched effects of athletes when using clenbuterol:
• Increase strength and endurance
• Improve breathing and body oxygen supply
• Psychic activation
• Increased fat burning in the body
• Reduction of appetite
• Anti-catabolic action
Mechanism of action and effects of clenbuterol intake Clenbuterol is a selective beta-2 agonist that structurally and pharmacologically resembles ephedrine and salbutamol as well as bronchodilators, but has a more pronounced
thermogenic and muscle-stimulating effect. This action is related to the fact that, besides the bronchi, it also acts on the beta2 receptors found on muscle, fat cells and the central nervous system. Thus used as doping, not only effects on the respiratory system, but also on the muscles, adipose tissue, brain and metabolism are sought. That is why in
bodybuilding environments, clenbuterol is known to be a preparation for increasing energy and activating thermogenesis.

Effects of clenbuterol on its effects on receptors on different tissues and organs: Activation of beta-2 receptors in the muscles increases the use of glucose, increases muscle strength, muscle contraction and thermogenesis. This leads to increased strength and durability and increased energy use in physically loaded. This effect is complemented by improved blood filling of muscles due to decreased vascular tone in skeletal muscles. Activation of beta-2 receptors in the liver increases glycolysis and secretion of glucose in the blood, which provides for long-term work of the muscles and is associated with increased endurance. Activation of beta-2 receptors in fat cells unleashes a biochemical reaction that results in increased synthesis of cAMP (cyclic adenosine monophosphate). This results in the release of fatty acids in the blood and the increase in lipolysis. The overall effect of this is accelerating metabolism and increasing fat burning from fat stores. Activation of beta-2 receptors in the central nervous system stimulates mental activity and indirectly increases thyroid secretion, which is also associated with increased metabolism and fat burning. Another feature of clenbuterol is that, along with its thermogenic effect, it also protects the breakdown of muscle tissue. This quality makes it a preferred tool during bodybuilding fat removal periods.
Most of these mechanisms associated with activation of beta receptors, our body uses in stress and to activate the physiological state of “fight or run” in order to get a quick burst of energy. This, however, occurs for a very short period of time and is related to the natural release of adrenaline, noradrenaline and activation of the sympathetic portion of the vegetative nervous system. However, when this effect is caused by drugs such as clenbuterol for an extended period of time, this can cause a number of side effects from the cardiovascular system, central nervous system and various organs. In addition, the prolonged use of such drugs is associated with saturation of the receptors
and reduction of their effects over time. This requires a significant dose increase to achieve the same effect. For this reason, athletes often significantly increase the dose, which further increases the risk of serious side effects and incidents.

clenbuterol sport, athlete, doping, soccer, cross-country skiing, boxing, swimming

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Sara Viesca

I have been researching and writing about Clenbuterol for the past years, and the subject has been fascinating for me. Many people has started to take clen and that's why i was interested to gather more information about the pills, its side effects, dosages, pros and cons. Send me any useful information you may have, so it might be published on the site.

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