Did Clenbuterol cause this heart attack ?

Clenbuterol remains a popular drug with many athletes, who believe that it provides both anabolic and fat-burning effects.
Clenbuterol is a beta-2 agonist mainly used to treat asthma. It was never approved for human use in the United States by the Food and Drug Administration but is available under various brand names in several countries, including Mexico. Drug companies have no interest in marketing clenbuterol in the USA because it lasts far longer in the body than other beta-2 agonist drugs, and its extended half-life, as it’s called, increases the chances of side effects. Since clenbuterol is based on epinephrine, it has side effects similar to those of epinephrine, including rapid heartbeat, nervousness, tremors, headache, muscle pain and gastrointestinal problems. In animals it provides a repartitioning effect, in that lean muscle mass increases while bodyfat is substantially lowered. That occurs in many animal species and explains why the drug proved attractive for athletic purposes. Some cases of clenbuterol tained meat have led to side-effect outbreaks in Europe, leading in turn to a European ban on clenbuterol for livestock purposes.

What many athletes didn’t consider, however, was that the doses of clenbuterol used in animal studies were far higher than could be tolerated by any human. The drug does provide potent-though fleeting-thermogenic effects, which is why it’s considered a “cutting” drug in bodybuilding. The adrenergic cell receptors that clenbuterol interacts with, however, are exquisitely sensitive and tend to close down within a short time, often with as little as two weeks of continuous use.

Athletes work around the considerable downregulation by taking it on a two-days-on/two-days-off pattern, which extends the usage time. Another technique involves using ketotifen (Zaditen), and antihistamine that can maintain the potency of adrenergic cell receptors, thereby extending the usefulness of clenbuterol.

Another thing to consider about clenbuterol is that several recent studies have confirmed that it produces severe toxic effects in muscle. In fact, some animal studies show that the drug appears to destroy muscle. The toxic effects are especially apparent in heart muscle.

According to a recent case study, in some people the effect may be potent enough to lead to a heart attach in an otherwise healthy person. Published reports have lined a combination of clenbuterol and anabolic steroids to a bodybuilder’s heart attack. The 26-year-old man in that case had switched to using clenbuterol after getting off a steroid cycle. His heart attack was attributed to a spasm of his coronary arteries.

In the newly reported case, the subject was a 17-year-old bodybuilder who claimed that he used no anabolic steroids or other drugs with the exception of 20 milligrams a day of clenbuterol, which he took on a two-days-on/two-days-off protocol. That’s not considered a high dose or frequency. Despite that, he turned up at a clinic complaining of acute chest pains. Examination showed that he had a fast heart rate and an elevated level of homocysteine, an amino acid by-product linked to cardiovascular disease. Most of his other tests were normal, although certain elevated enzyme levels pointed to heart damage.

His diagnosis was that of a clenbuterol-induced coronary artery spasm, with possible blood clot in the left anterior descending coronary artery, the most common area of blood clots leading to heart attacks. The case was complicated, however, because the subject had two risk factors linked to the onset of coronary artery spasms-elevated homocysteine levels and increased clotting elements in the blood. Homocysteine is easily controlled in most cases by taking three nutrients: folic acid, and vitamins B6 and B12. The clotting can be controlled by small daily doses of aspirin, which he was given.

The question, then, is whether the heart attack was caused by clenbuterol or his other risk factors. Most likely it was a combination. The adrenergic effect of clenbuterol may have pushed him over the edge. One thing is certain, however: Clenbuterol, even in small amounts, exerts toxic effects on heart muscle tissue. It could cause serious heart problems in anyone. Combining clenbuterol with other thermogenic drugs, such as thyroid hormone, compounds the effect because TH in large doses also stresses the heart. The combination of the two could prove deadly.

In fact clenbuterol and TH use are likely suspects in the death of a professional bodybuilder several years ago. This man was using large doses of TH and an injectable form of clenbuterol. He was also dehydrated and probably suffering an electrolyte, or mineral, imbalance. With that many things against him, it wasn’t surprising that he succumbed to a heart attack.




Did Clenbuterol cause this heart attack, clen heart attack, clenbuterol and TH, clenbuterol risk factors, clenbuterol artery spasm, clenbuterol and anabolic steroids, Homocysteine

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Sara Viesca

I have been researching and writing about Clenbuterol for the past years, and the subject has been fascinating for me. Many people has started to take clen and that's why i was interested to gather more information about the pills, its side effects, dosages, pros and cons. Send me any useful information you may have, so it might be published on the site.

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